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KMID : 1007520190280010209
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Food Science and Biotechnology
2019 Volume.28 No. 1 p.209 ~ p.214
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Antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium from a Jeju water concentrate
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Yun Ji-Hyun
Park Sung-Hwan
Choi Goo-Hee
Park In-Jae
Lee Jin-Ha
Lee Ok-Hwan
Kim Jung-Hyon
Seo Yun-Hee
Cho Ju-Hyun
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Abstract
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The purpose of this study was to determine the antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium (BECV). The BECV was prepared following nutriculture of B. napus with a Jeju water vanadium concentrate for 7 day. The BECV was administered to db/db mice for 8 weeks at different dosages (0.028, 0.14, and 0.7 μg/kg; as vanadium concentration in BECV). After 8 weeks, the BECV results showed mouse blood glucose concentrations to significantly decrease, in a dose-dependent manner, compared with the results for control mice. In addition, the concentrations of triglyceride, total cholesterol, and glycated hemoglobin were significantly lower after 8 weeks of administration of 0.7 μg/kg BECV. Therefore, the BECV may have protective effects against type 2 diabetes.
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KEYWORD
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Vanadium, Brassica napus extract, Antidiabetic effect, db/db mouse
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